Ksr2 Polyclonal Antibody, 100ul Cell Proliferation Three of the transcript variants

Three of the transcript variants are supported by experimental evidence and the fourth contains alternate 5' untranslated exons

This gene encodes a bifunctional signal transduction molecule

Also expressed in Barrett's esophagus epithelium and in the proximal duodenum

Acts as a GTPase activitor in vitro for CDC42 and RAC1

The encoded protein regulates erythroid gene expression| plays a role in the transcriptional switch of globin gene promoters| and it activates many other cellular and viral gene promoters

Ksr2 Polyclonal Antibody, 100ul Cell Proliferation Three of the transcript variantsLocation regulated scaffold connecting MEK to RAF. Blocks MAP3K8 kinase activity and MAP3K8 mediated signaling. Acts as a negative regulator of MAP3K3 mediated activation of ERK, JNK and NF kappa B pathways, inhibiting MAP3K3 mediated interleukin 8 production.