O-FucT-2 Polyclonal Antibody, 20ul Contamination Detection & Removal Multiple alternatively spliced transcript variants

Multiple alternatively spliced transcript variants encoding different isoforms have been identified in CD4

The encoded protein appears to interact with Rh blood group antigens and Rh30 polypeptides

and its expression is upregulated in several kinds of carcinomas

APOBEC4 encodes a member of the AID/APOBEC family of polynucleotide (deoxy)cytidine deaminases

These products include the cathepsin B light and heavy chains

O-FucT-2 Polyclonal Antibody, 20ul Contamination Detection & Removal Multiple alternatively spliced transcript variantsFucose is typically found as a terminal modification of branched chain glycoconjugates, but it also exists in direct O linkage to serine or threonine residues within cystine knot motifs in epidermal growth factor (EGF; MIM 131530) like repeats or thrombospondin (THBS; see MIM 188060) type 1 repeats. POFUT2 is an O fucosyltransferase that use THBS type 1 repeats as substrates (Luo et al. 2006 [PubMed 16464857]).