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DUS26 Polyclonal Antibody, 100ul Cryogenic Vials The RB1 gene product is

SKU: 52311600320

4.1
USD123.75 USD156.75

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DUS26 Polyclonal Antibody, 100ul Cryogenic Vials The RB1 gene product isThis gene encodes a member of the tyrosine phosphatase family of proteins and exhibits dual specificity by dephosphorylating tyrosine as well as serine and threonine residues. This gene has been described as both a tumor suppressor and an oncogene depending on the cellular context. This protein may regulate neuronal proliferation and has been implicated in the progression of glioblastoma through its ability to dephosphorylate the p53 tumor suppressor.

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Description

The RB1 gene product is a tumor suppressor protein that appears to be involved in cell cycle regulation

growth cone guidance

they ensure optimal growth and maintenance of cells

Alternatively spliced transcript variants have been observed but the full-length nature of only one has been determined

which are involved in DNA binding and protein-protein interactions

DUS26 Polyclonal Antibody, 100ul Cryogenic Vials The RB1 gene product isThis gene encodes a member of the tyrosine phosphatase family of proteins and exhibits dual specificity by dephosphorylating tyrosine as well as serine and threonine residues. This gene has been described as both a tumor suppressor and an oncogene depending on the cellular context. This protein may regulate neuronal proliferation and has been implicated in the progression of glioblastoma through its ability to dephosphorylate the p53 tumor suppressor.

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