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AR Polyclonal Antibody, 20ul[BT-AP00399] Fluorescent Staining While all introns in the

SKU: 4993808773

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AR Polyclonal Antibody, 20ul[BT-AP00399] Fluorescent Staining While all introns in theThe androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N terminal domain, DNA binding domain, and androgen binding domain. The protein functions as a steroid hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This

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Description

While all introns in the coding sequence have been processed out compared to the RBMX locus| the ORF is intact and there is specific evidence for transcription at this location

Interacts with DNTTIP2| FAM120B and UIMC1

It can also associate with two heat shock proteins (hsp90 and hsp70) and thus may play a role in the intracellular trafficking of hetero-oligomeric forms of the steroid hormone receptors

It is a receptor for the CC chemokine - MIP-1

CUL2 not CUL3

AR Polyclonal Antibody, 20ul[BT-AP00399] Fluorescent Staining While all introns in theThe androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N terminal domain, DNA binding domain, and androgen binding domain. The protein functions as a steroid hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This

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