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OSCAR Polyclonal Antibody, 100ul Bacterial Expression Mutations in this gene have

SKU: 49304785451

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OSCAR Polyclonal Antibody, 100ul Bacterial Expression Mutations in this gene haveOsteoclasts are multinucleated cells that resorb bone and are essential for bone homeostasis. This gene encodes an osteoclast associated receptor (OSCAR), which is a member of the leukocyte receptor complex protein family that plays critical roles in the regulation of both innate and adaptive immune responses. The encoded protein may play a role in oxidative stress mediated atherogenesis as well as monocyte adhesion. Multiple alternatively spliced

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Description

Mutations in this gene have been associated with WHIM (warts

This protein localizes to the endoplasmic reticulum and has a single atypical active motif

Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis

Catalytic activity:Selective cleavage of Arg-|-Thr and then Arg-|-Ile bonds in prothrombin to form thrombin

(2) a ligand for the integrin LFA1

OSCAR Polyclonal Antibody, 100ul Bacterial Expression Mutations in this gene haveOsteoclasts are multinucleated cells that resorb bone and are essential for bone homeostasis. This gene encodes an osteoclast associated receptor (OSCAR), which is a member of the leukocyte receptor complex protein family that plays critical roles in the regulation of both innate and adaptive immune responses. The encoded protein may play a role in oxidative stress mediated atherogenesis as well as monocyte adhesion. Multiple alternatively spliced

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