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Raf-1 Polyclonal Antibody, 20ul[BT-AP13537] Yeast Expression suggesting a link with Alzheimer

SKU: 48872158729

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PLN111.00 PLN141.00

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Raf-1 Polyclonal Antibody, 20ul[BT-AP13537] Yeast Expression suggesting a link with AlzheimerThis gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.

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Description

suggesting a link with Alzheimer disease

Extracellularly

The protein encoded by CCNB1 (cyclin B1) is a regulatory protein involved in mitosis

Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized

The catalytic portion of mitochondrial ATP synthase consists of five different subunits (alpha| beta| gamma| delta| and epsilon) assembled with a stoichiometry of 3 alpha| 3 beta| and single representatives of the gamma| delta| and epsilon subunits

Raf-1 Polyclonal Antibody, 20ul[BT-AP13537] Yeast Expression suggesting a link with AlzheimerThis gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.

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