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Rev-erb alpha(Phospho-Ser55/59) Rabbit Polyclonal Antibody, 50ul Immunology Mutations in this gene are

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Rev-erb alpha(Phospho-Ser55/59) Rabbit Polyclonal Antibody, 50ul Immunology Mutations in this gene areThis gene encodes a transcription factor that is a member of the nuclear receptor subfamily 1. The encoded protein is a ligand sensitive transcription factor that negatively regulates the expression of core clock proteins. In particular this protein represses the circadian clock transcription factor aryl hydrocarbon receptor nuclear translocator like protein 1 (ARNTL). This protein may also be involved in regulating genes that function in metabolic

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Description

Mutations in this gene are associated with multiple epiphyseal dysplasia

This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9

They also reduce the mitochondrial membrane potential in mammalian cells

This pharmacological effect requires nicotinic acid doses that are much higher than those provided by a normal diet

The protein encoded by this gene is a member of the Ig superfamily of cell adhesion molecules and is involved in neuronal differentiation

Rev-erb alpha(Phospho-Ser55/59) Rabbit Polyclonal Antibody, 50ul Immunology Mutations in this gene areThis gene encodes a transcription factor that is a member of the nuclear receptor subfamily 1. The encoded protein is a ligand sensitive transcription factor that negatively regulates the expression of core clock proteins. In particular this protein represses the circadian clock transcription factor aryl hydrocarbon receptor nuclear translocator like protein 1 (ARNTL). This protein may also be involved in regulating genes that function in metabolic

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