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UBP6 Polyclonal Antibody, 50ul sgRNA Oligos Alternative splicing of PITPNB results

SKU: 48342016254

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UBP6 Polyclonal Antibody, 50ul sgRNA Oligos Alternative splicing of PITPNB resultsCatalytic activity: Ubiquitin C terminal thioester + H(2)O = ubiquitin + a thiol.,disease: Involved in tumorigenesis.,Has an ATP independent isopeptidase activity, cleaving at the C terminus of the ubiquitin moiety. In vitro, isoform 2, but not isoform 3, shows deubiquitinating activity.,miscellaneous: The USP6 gene only exists in the primate lineage.,Belongs to the peptidase C19 family.,Contains 1 Rab GAP TBC domain.,tissue specificity: Testis

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Description

Alternative splicing of PITPNB results in multiple transcript variants

The encoded protein functions through direct interaction with target mRNAs and by disrupting the maturation of certain miRNAs involved in embryonic development

Among its related pathways are Gene Expression and Cell Cycle

an alternative non-homologous end-joining (NHEJ) machinery triggered in response to double-strand breaks in DNA (PubMed: 25642963

CEP41 (centrosomal protein 41) encodes a centrosomal and microtubule-binding protein which is predicted to have two coiled-coil domains and a rhodanese domain

UBP6 Polyclonal Antibody, 50ul sgRNA Oligos Alternative splicing of PITPNB resultsCatalytic activity: Ubiquitin C terminal thioester + H(2)O = ubiquitin + a thiol.,disease: Involved in tumorigenesis.,Has an ATP independent isopeptidase activity, cleaving at the C terminus of the ubiquitin moiety. In vitro, isoform 2, but not isoform 3, shows deubiquitinating activity.,miscellaneous: The USP6 gene only exists in the primate lineage.,Belongs to the peptidase C19 family.,Contains 1 Rab GAP TBC domain.,tissue specificity: Testis

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