SH3B4 Polyclonal Antibody, 100ul Liquid Handling ＆Storage Two alternatively spliced transcript variants

Two alternatively spliced transcript variants encoding different isoforms have been observed

which enables it to act as a GTPase activating protein (GAP) for the Arf family of GTPases

which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle

Can inhibit secretion of soluble proteins

This protein may function in motility

SH3B4 Polyclonal Antibody, 100ul Liquid Handling ＆Storage Two alternatively spliced transcript variantsThis gene encodes a protein with 3 Asn Pro Phe (NPF) motifs, an SH3 domain, a PXXP motif, a bipartite nuclear targeting signal, and a tyrosine phosphorylation site. This protein is involved in cargo specific control of clathrin mediated endocytosis, specifically controlling the internalization of a specific protein receptor.