DKK4 Polyclonal Antibody, 20ul Vector Construction LMNB1 encodes one of the

LMNB1 encodes one of the two B-type lamin proteins and is a component of the nuclear lamina

Studies in mouse suggest that this gene plays an important role in cardiac muscle development

in embryonic and tumor angiogenesis and as a human immunodeficiency virus (HIV-1) coreceptor

Overexpression of this gene suppresses the activation of NF-kappa B induced by TNFRSF9 or TNF receptor-associated factor 2 (TRAF2)| which suggests that this protein is a negative regulator of TNFRSF9-mediated signaling cascades

is secreted by activated T cells and displays chemotactic activity for monocytes but not for neutrophils

DKK4 Polyclonal Antibody, 20ul Vector Construction LMNB1 encodes one of theThis gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. Activity of this protein is modulated by binding to the Wnt co receptor and the co factor kremen 2.