ERCC1 Monoclonal Antibody(1B10), 50ul Molecular Sciences The protein encoded by this

The protein encoded by this gene is a member of the family of voltage-gated chloride channels

It is a typical serine proteinase with trypsin-like specificity

This protein is a membrane-bound ubiquitin ligase

This gene encodes a member of a small calcium-binding EF-hand protein family

contains a transmembrane domain and is expressed at the cell surface

ERCC1 Monoclonal Antibody(1B10), 50ul Molecular Sciences The protein encoded by thisThe product of this gene functions in the nucleotide excision repair pathway, and is required for the repair of DNA lesions such as those induced by UV light or formed by electrophilic compounds including cisplatin. The encoded protein forms a heterodimer with the XPF endonuclease (also known as ERCC4), and the heterodimeric endonuclease catalyzes the 5' incision in the process of excising the DNA lesion. The heterodimeric endonuclease is also