MLH3 Polyclonal Antibody, 100ul 3D Cell Culture Consumables The enzyme plays a role

The enzyme plays a role in several pathophysiological processes including hemostasis

Mutations in RYR2 are associated with stress-induced polymorphic ventricular tachycardia and arrhythmogenic right ventricular dysplasia

particularly in cells of the myeloid and B-lymphoid lineages

Mutations in this gene have also been associated with various cancers

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MLH3 Polyclonal Antibody, 100ul 3D Cell Culture Consumables The enzyme plays a roleMLH3 is a member of the MutL homolog (MLH) family of DNA mismatch repair (MMR) genes. MLH genes are implicated in maintaining genomic integrity during DNA replication and after meiotic recombination. The mutL homolog 3 encoded by MLH3 functions as a heterodimer with other family members. Somatic mutations in this gene frequently occur in tumors exhibiting microsatellite instability, and germline mutations have been linked to hereditary nonpolyposis