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Integrin Alpha 4 Polyclonal Antibody, 20ul Cell Function Analysis Mutations in this gene are

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Integrin Alpha 4 Polyclonal Antibody, 20ul Cell Function Analysis Mutations in this gene areITGA4 encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 4 subunit. This subunit associates with a beta 1 or beta 7 subunit to form an integrin that may play a role in cell

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Description

Mutations in this gene are associated with an autosomal dominant form of hereditary fibrosing poikiloderma (HFP)

An important paralog of this gene is COL8A1

The erythrocyte form is located in a soluble fraction of circulating erythrocytes and is involved in methemoglobin reduction

GO annotations related to this gene include protein kinase binding

It is part of the gamma tubulin complex

Integrin Alpha 4 Polyclonal Antibody, 20ul Cell Function Analysis Mutations in this gene areITGA4 encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 4 subunit. This subunit associates with a beta 1 or beta 7 subunit to form an integrin that may play a role in cell

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