SPP2A Rabbit Polyclonal Antibody, 20ul ssDNA Synthesis Associates with the 9-1-1 complex

Associates with the 9-1-1 complex

is a 683 amino acid protein

The beta and gamma actins co-exist in most cell types as components of the cytoskeleton and as mediators of internal cell motility

Patients with dermatomyositis develop antibodies against this protein

concurrently establish local embryonic retinoic acid levels which facilitate posterior organ development and prevent spina bifida

SPP2A Rabbit Polyclonal Antibody, 20ul ssDNA Synthesis Associates with the 9-1-1 complexThis gene encodes a member of the GXGD family of aspartic proteases which are transmembrane proteins with two conserved catalytic motifs localized within the membrane spanning regions as well as a member of the signal peptide peptidase like protease (SPPL) family. This protein is expressed in all major adult human tissues and localizes to late endosomal compartments and lysosomal membranes. A pseudogene of this gene also lies on chromosome 15.