Phospho-BLM (T99) Polyclonal Antibody, 100ul DNA Oligo Synthesis Mutations in this gene have

Mutations in this gene have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy

a transmembrane domain and a cytoplasmic domain that contains three immune-receptor tyrosine-based inhibitory motifs

This gene encodes a member of the TWIK-related arachidonic acid-stimulated two pore potassium channel subfamily

The deficient mice exhibited defects in early differentiation of T and B lymphocytes

Expression in glioblastomas is highly variable

Phospho-BLM (T99) Polyclonal Antibody, 100ul DNA Oligo Synthesis Mutations in this gene haveThe Bloom syndrome gene product is related to the RecQ subset of DExH box containing DNA helicases and has both DNA stimulated ATPase and ATP dependent DNA helicase activities. Mutations causing Bloom syndrome delete or alter helicase motifs and may disable the 3' 5' helicase activity. The normal protein may act to suppress inappropriate recombination.