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CBX2 Polyclonal Antibody, 50ul CellSafe™ Polymorphisms resulting in amino acid

SKU: 4282314941

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CBX2 Polyclonal Antibody, 50ul CellSafe™ Polymorphisms resulting in amino acidCBX2 (chromobox 2) encodes a component of the polycomb multiprotein complex, which is required to maintain the transcriptionally repressive state of many genes throughout development via chromatin remodeling and modification of histones. Disruption of CBX2 in mice results in male to female gonadal sex reversal. Mutations in CBX2 are also associated with gonadal dysgenesis in humans. Alternatively spliced transcript variants encoding different isoforms

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Description

Polymorphisms resulting in amino acid substitutions in these two subunits have been associated with the regulation of blood pressure in an animal model of hypertension

The presence of a putative bipartite nuclear localization signal suggests that this gene encodes a nuclear protein

Customizable user setting program with up to 6 sequential steps

The product of this gene is an enzyme involved in lipid metabolism| and it encodes cytosolic acetoacetyl-CoA thiolase

and it is part of a duplicated region of chromosome 1p36

CBX2 Polyclonal Antibody, 50ul CellSafe™ Polymorphisms resulting in amino acidCBX2 (chromobox 2) encodes a component of the polycomb multiprotein complex, which is required to maintain the transcriptionally repressive state of many genes throughout development via chromatin remodeling and modification of histones. Disruption of CBX2 in mice results in male to female gonadal sex reversal. Mutations in CBX2 are also associated with gonadal dysgenesis in humans. Alternatively spliced transcript variants encoding different isoforms

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