Synuclein-alpha(Phospho Tyr125) Polyclonal Antibody, 50ul Cellular Function Assays TEP1 (telomerase associated protein 1)product

TEP1 (telomerase associated protein 1)product is a component of the ribonucleoprotein complex responsible for telomerase activity which catalyzes the addition of new telomeres on the chromosome ends

which may play a role in the response to environmental stress

It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic

This gene is aberrantly methylated in pancreatic cancer

MIM 114180)-dependent PDEs (CaM-PDEs) that are activated by calmodulin in the presence of Ca(2+) (Michibata et al

Synuclein-alpha(Phospho Tyr125) Polyclonal Antibody, 50ul Cellular Function Assays TEP1 (telomerase associated protein 1)productAlpha synuclein is a member of the synuclein family, which also includes beta and gamma synuclein. Synucleins are abundantly expressed in the brain and alpha and beta synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with