APC1 Polyclonal Antibody, 100ul[BT-AP00510] Enzyme Activity Assays Mixed lineage kinase domain-like protein

Mixed lineage kinase domain-like protein plays a critical role in tumor necrosis factor (TNF)-induced necroptosis

Certain mutations in this gene resulting in a functionally inadequate enzyme are associated with a rare genetic disorder causing nonspherocytic hemolytic anemia

Desumoylated by SENP2

dimethylallyl diphosphate (DMAPP)

May play a role in the uptake and recycling of iron| via endocytosis of hemoglobin/haptoglobin and subsequent breakdown of heme

APC1 Polyclonal Antibody, 100ul[BT-AP00510] Enzyme Activity Assays Mixed lineage kinase domain-like proteinANAPC1 encodes a subunit of the anaphase promoting complex. This complex (anaphase promoting complex subunit 1) is an E3 ubiquitin ligase that regulates progression through the metaphase to anaphase portion of the cell cycle by ubiquitinating proteins which targets them for degradation.