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CYLD(Phospho-Ser418) Rabbit Polyclonal Antibody, 50ul Cell Separation and Collection CCT8 encodes the theta subunit

SKU: 42391466185

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CYLD(Phospho-Ser418) Rabbit Polyclonal Antibody, 50ul Cell Separation and Collection CCT8 encodes the theta subunitThis gene is encodes a cytoplasmic protein with three cytoskeletal associated protein glycine conserved (CAP GLY) domains that functions as a deubiquitinating enzyme. Mutations in this gene have been associated with cylindromatosis multiple familial trichoepithelioma and Brooke Spiegler syndrome. Alternate transcriptional splice variants encoding different isoforms have been characterized.

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Description

CCT8 encodes the theta subunit of the CCT chaperonin

A second breast cancer susceptibility gene

The expression of this gene is induced by various cytokines

ADULT syndrome (acro-dermato-ungual-lacrimal-tooth)

BCAS2 may thus be potentially useful as a therapeutic target in the treatment of cancer

CYLD(Phospho-Ser418) Rabbit Polyclonal Antibody, 50ul Cell Separation and Collection CCT8 encodes the theta subunitThis gene is encodes a cytoplasmic protein with three cytoskeletal associated protein glycine conserved (CAP GLY) domains that functions as a deubiquitinating enzyme. Mutations in this gene have been associated with cylindromatosis multiple familial trichoepithelioma and Brooke Spiegler syndrome. Alternate transcriptional splice variants encoding different isoforms have been characterized.

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