CCNK Polyclonal Antibody, 100ul Supplements Poly [ADP-ribose] polymerase 2 has

Poly [ADP-ribose] polymerase 2 has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase

This gene encodes an enzyme which catalyzes the translocation of the Man(5)GlcNAc (2)-PP-Dol intermediate from the cytoplasmic to the luminal side of the endoplasmic reticulum membrane in the pathway for the N-glycosylation of proteins

suggesting that it is required to connect RNA polymerase II to regulators of protein complex formation

The absence of CA8 gene transcription in the cerebellum of the lurcher mutant in mice with a neurologic defect suggests an important role for this acatalytic form

gene conversion

CCNK Polyclonal Antibody, 100ul Supplements Poly [ADP-ribose] polymerase 2 hasThe protein encoded by this gene is a member of the transcription cyclin family. These cyclins may regulate transcription through their association with and activation of cyclin dependent kinases (CDK) that phosphorylate the C terminal domain (CTD) of the large subunit of RNA polymerase II. This gene product may play a dual role in regulating CDK and RNA polymerase II activities.