Uba5 Polyclonal Antibody, 50ul Fluorescent Staining ERAS encodes a constitutively active

ERAS encodes a constitutively active member of the small GTPase Ras protein family

tissue specificity:Expressed in brain and kidney

Overexpression of this gene has been shown to suppress cell apoptosis possibly through the prevention of cytochrome C release from the mitochondria

Unlike other members of the family

TPases are a group of enzymes that catalyze hydrolysis of the gamma phosphate bond in guanine triphosphate (GTP) to form guanine diphosphate (GDP)

Uba5 Polyclonal Antibody, 50ul Fluorescent Staining ERAS encodes a constitutively activeUBA5 encodes a member of the E1 like ubiquitin activating enzyme family. Ubiquitin like modifier activating enzyme 5 activates ubiquitin fold modifier 1, a ubiquitin like post translational modifier protein, via the formation of a high energy thioester bond. Alternative splicing results in multiple transcript variants. A pseudogene of this gene has been identified on chromosome 1.