NuMA Polyclonal Antibody, 50ul High Speed Micro-Centrifuges Mutations in the gene are

Mutations in the gene are associated with localized autosomal recessive hypotrichosis and monilethrix

depending on stage of neuronal maturation and neuron type

and like them may bind the catalytic subunit of DNA-dependent protein kinases

Involved in formation of membrane ruffles and lamellipodia protrusions and in axon outgrowth

Mutations in this gene have been associated with geroderma osteodysplastica

NuMA Polyclonal Antibody, 50ul High Speed Micro-Centrifuges Mutations in the gene areNUMA1 encodes a large protein that forms a structural component of the nuclear matrix. The encoded protein interacts with microtubules and plays a role in the formation and organization of the mitotic spindle during cell division. Chromosomal translocation of NUMA1 with the RARA (retinoic acid receptor, alpha) gene on chromosome 17 have been detected in patients with acute promyelocytic leukemia. Alternative splicing results in multiple transcript