GRK2(Phospho-Tyr86) Polyclonal Antibody, 100ul Antibody Humanization Cyclin F encoded by CCNF

Cyclin F encoded by CCNF belongs to the Fbxs class and it was one of the first proteins in which the F-box motif was identified

also known as BCSC-1 (breast cancer suppressor candidate 1) or LOH11CR2A (loss of heterozygosity 11 chromosomal region 2 gene A protein)

2006 [PubMed 16326147])

Insulin-like growth factor 1 receptor binds insulin-like growth factor with a high affinity

embryogenesis

GRK2(Phospho-Tyr86) Polyclonal Antibody, 100ul Antibody Humanization Cyclin F encoded by CCNFThe product of this gene phosphorylates the beta 2 adrenergic receptor and appears to mediate agonist specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta adrenergic and related G protein coupled receptors. Abnormal coupling of beta adrenergic receptor to G protein is involved in the pathogenesis of the failing heart.