ALKB3 Polyclonal Antibody, 50ul Adeno-associated Virus Packaging Aberrant expression of NKX3-1 is

Aberrant expression of NKX3-1 is associated with prostate tumor progression

This gene contains sequences homologous to several motifs that are shared among some nuclear genes encoding mitochondrial proteins and thus may be essential for the coordinated activation of these genes during mitochondrial biogenesis

Mutations in this gene cause cryptogenic cirrhosis

Contains 3 Ig-like C2-type (immunoglobulin-like) domains

Pseudogenes corresponding to this gene are found on chromosomes 2p

ALKB3 Polyclonal Antibody, 50ul Adeno-associated Virus Packaging Aberrant expression of NKX3-1 isThe Escherichia coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single stranded DNA. ALKBH2 (MIM 610602) and ALKBH3 are E. coli AlkB homologs that catalyze the removal of 1 methyladenine and 3 methylcytosine (Duncan et al., 2002