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FAK(Phospho Tyr861) Polyclonal Antibody, 50ul Custom DNA Oligos and 2 laminin-type EGF-like domains

SKU: 38457118324

4.2
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FAK(Phospho Tyr861) Polyclonal Antibody, 50ul Custom DNA Oligos and 2 laminin-type EGF-like domainsThis gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal

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Description

and 2 laminin-type EGF-like domains as well as a C-type lectin-like hyaluronan-binding Link module

suggesting a cell cycle function

Also detected in hepatoblastoma HepG2 cells

with the last serine residue replaced by alanine

P311 regulates retinoic-acid lipid-droplet biogenesis

FAK(Phospho Tyr861) Polyclonal Antibody, 50ul Custom DNA Oligos and 2 laminin-type EGF-like domainsThis gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal

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