CD109 Polyclonal Antibody, 20ul Vector Construction which is required for TNF-alpha-mediated

which is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB

High levels also detected in liver

This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor| all three genes may be implicated in the 5-q syndrome

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The protein encoded by this gene belongs to the EGR family of C2H2-type zinc-finger proteins

CD109 Polyclonal Antibody, 20ul Vector Construction which is required for TNF-alpha-mediatedThis gene encodes a glycosyl phosphatidylinositol (GPI) linked glycoprotein that localizes to the surface of platelets, activated T cells, and endothelial cells. The protein binds to and negatively regulates signalling by transforming growth factor beta (TGF beta). Multiple transcript variants encoding different isoforms have been found for this gene.