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LKB1 Polyclonal Antibody, 100ul[BT-AP05039] Molecular Sciences but appear to have divergent

SKU: 3606051335

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LKB1 Polyclonal Antibody, 100ul[BT-AP05039] Molecular Sciences but appear to have divergentSTK11 (serine threonine kinase 11), which encodes a member of the serine threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in STK11 have been associated with Peutz Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms. Alternate transcriptional splice variants of STK11 have been

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Description

but appear to have divergent biological functions

7-transmembrane receptor (GPCR) superfamily

Cyclin dependent kinase 11B encoded by CDK11B can be cleaved by caspases and may play a role in cell apoptosis

and a key role in cardiovascular homeostasis

|PTM:Constitutively sumoylated by SUMO1| SUMO2 and SUMO3

LKB1 Polyclonal Antibody, 100ul[BT-AP05039] Molecular Sciences but appear to have divergentSTK11 (serine threonine kinase 11), which encodes a member of the serine threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in STK11 have been associated with Peutz Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms. Alternate transcriptional splice variants of STK11 have been

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