MC2-R Polyclonal Antibody, 20ul sgRNA customized design It is localized in the

It is localized in the speckle domains of the nucleus

Alternatively spliced transcript variants encoding distinct isoforms exist

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MC2-R Polyclonal Antibody, 20ul sgRNA customized design It is localized in theMC2R encodes one member of the five member G protein associated melanocortin receptor family. Melanocortins (melanocyte stimulating hormones and adrenocorticotropic hormone) are peptides derived from pro opiomelanocortin (POMC). MC2R is selectively activated by adrenocorticotropic hormone, whereas the other four melanocortin receptors recognize a variety of melanocortin ligands. Mutations in MC2R can result in familial glucocorticoid deficiency.