GPTC8 Polyclonal Antibody, 50ul Molecular Biology The type VII collagen fibril

The type VII collagen fibril

and is involved in muscular excitation and contraction

and neonatal respiratory distress

One isoform lacks the intermembrane region and is secreted outside the cell

The protein encoded by this gene is a lymphocyte-expressed ADAM protein

GPTC8 Polyclonal Antibody, 50ul Molecular Biology The type VII collagen fibrilThe protein encoded by this gene contains an RNA processing domain, a zinc finger domain, a lysine rich region and a serine rich region. A mutation in the serine rich region of the protein is thought to be associated with hyperuricemia (PMID: 21594610). Alternative splicing results in multiple transcript variants encoding different isoforms.