EWS Polyclonal Antibody, 100ul Cryogenic Vials Filamin-A is involved in remodeling

Filamin-A is involved in remodeling the cytoskeleton to effect changes in cell shape and migration

It is known to bind the US-2 DNA element in the promoter of the oxytocin receptor (OTR) gene and most likely heterodimerizes with other leucine zipper-containing proteins to enhance expression of the OTR gene during term pregnancy

The protein encoded by this gene belongs to the TYR family of protein kinases

designated Q20*) which blocks expression of this protein

and carcinogenesis

EWS Polyclonal Antibody, 100ul Cryogenic Vials Filamin-A is involved in remodelingEWSR1 encodes a multifunctional protein that is involved in various cellular processes, including gene expression, cell signaling, and RNA processing and transport. The protein includes an N terminal transcriptional activation domain and a C terminal RNA binding domain. Chromosomal translocations between this gene and various genes encoding transcription factors result in the production of chimeric proteins that are involved in tumorigenesis. These