p53(Phospho Ser6) Polyclonal Antibody, 20ul Apoptosis & Autophagy The protein has 7 transmembrane

The protein has 7 transmembrane regions and is located on the cell surface

This protein co-localizes with the RNA-binding protein pumilio RNA-binding family member 2 and may be involved in regulating translation as a post-transcriptional repressor

When overexpressed in mammalian cells

Knockout studies in mice suggest that the different receptors

This protein binds to chromatin prior to DNA damage and is phosphorylated by the checkpoint kinase ATR following damage

p53(Phospho Ser6) Polyclonal Antibody, 20ul Apoptosis & Autophagy The protein has 7 transmembraneThis gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.