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GCKR Polyclonal Antibody, 100ul Low retention tips Alternative splicing results in multiple

SKU: 32078648149

4.5
SEK141.00 SEK185.00

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GCKR Polyclonal Antibody, 100ul Low retention tips Alternative splicing results in multipleGCKR encodes glucokinase regulator belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non covalently to form an inactive complex with the enzyme. GCKR is considered a susceptibility gene candidate for a form of maturity onset diabetes of the young (MODY).

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Description

Alternative splicing results in multiple transcripts variants

Can also oxidize N(1)-acetylspermidine to putrescine

The protein encoded by BAX belongs to the BCL2 protein family

Overexpression of this gene in mammalian cells conferred a transformed phenotype

which is activated downstream of the Notch pathway

GCKR Polyclonal Antibody, 100ul Low retention tips Alternative splicing results in multipleGCKR encodes glucokinase regulator belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non covalently to form an inactive complex with the enzyme. GCKR is considered a susceptibility gene candidate for a form of maturity onset diabetes of the young (MODY).

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