E2F-3 (Acetyl-Lys168) Polyclonal Antibody, 100ul Fluorescent Staining Multiple mutations in this gene

Multiple mutations in this gene have been identified

The encoded protein binds directly to retinoblastoma protein

This gene encodes s receptor in the endoplasmic reticulum

some of which are associated with Creutzfeldt-Jakob disease

Defects in PRF1 cause familial hemophagocytic lymphohistiocytosis type 2 (HPLH2)

E2F-3 (Acetyl-Lys168) Polyclonal Antibody, 100ul Fluorescent Staining Multiple mutations in this geneE2F3 (E2F transcription factor 3) encodes a member of a small family of transcription factors that function through binding of DP interaction partner proteins. The encoded protein recognizes a specific sequence motif in DNA and interacts directly with the retinoblastoma protein (pRB) to regulate the expression of genes involved in the cell cycle. Altered copy number and activity of this gene have been observed in a number of human cancers. There are