SH2D5 Polyclonal Antibody, 50ul Protein Expression Both the human and orthologous

Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellular localization) resulting from the use of alternative in-frame translation initiation codons

Mutations in this gene result in trifunctional protein deficiency or LCHAD deficiency

suggesting that it plays a regulatory role in the translation apparatus

The encoded protein (A-kinase anchoring protein 5) binds to the RII-beta regulatory subunit of PKA

and to lead to NF-kappaB and MAPK8/JNK activation

SH2D5 Polyclonal Antibody, 50ul Protein Expression Both the human and orthologousSH2D5 (SH2 Domain Containing 5) is a Protein Coding gene. May be involved in synaptic plasticity regulation through the control of Rac GTP levels.