PFD4 Rabbit Polyclonal Antibody, 50ul Buffers & Solutions Quality control in the endoplasmic

Quality control in the endoplasmic reticulum (ER) ensures that only properly folded proteins are retained in the cell through recognition and degradation of misfolded or unassembled proteins

but it has not been determined whether this form is normal or due to aberrant splicing

The C-terminus contains binding sites for proteins such as beta-1-integrin

Involved in the activation of MAP kinases

recruiting a serine kinase which phosphorylates both itself and MLF1

PFD4 Rabbit Polyclonal Antibody, 50ul Buffers & Solutions Quality control in the endoplasmicThis gene encodes a member of the prefoldin beta subunit family. The encoded protein is one of six subunits of prefoldin a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides thereby allowing them to fold correctly. The complex consisting of two alpha and four beta subunits forms a double beta barrel assembly with six protruding coiled coils.