UBCE7IP4 Polyclonal Antibody, 20ul Bio-Reaction Tube WEE1 (WEE1 G2 checkpoint kinase)

WEE1 (WEE1 G2 checkpoint kinase) encodes a nuclear protein

exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail

that encodes an orphan G protein-coupled receptor

Germline mutations of the extracellular domains of this receptor were found to be associated with the autosomal dominant periodic fever syndrome

Negatively regulates aortic matrix metalloproteinase-9 (MMP9) production and may play a protective role in vascular remodeling

UBCE7IP4 Polyclonal Antibody, 20ul Bio-Reaction Tube WEE1 (WEE1 G2 checkpoint kinase)Probable E3 ubiquitin protein ligase RNF144A encoded by this protein contains a RING finger, a motif known to be involved in protein DNA and protein protein interactions. The mouse counterpart of this protein has been shown to interact with Ube2l3 UbcM4, which is an ubiquitin conjugating enzyme involved in embryonic development.