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VHL Polyclonal Antibody, 20ul[BT-AP09520] Vortex Mixer and murine studies suggest a

SKU: 29869313664

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SEK111.00 SEK147.00

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VHL Polyclonal Antibody, 20ul[BT-AP09520] Vortex Mixer and murine studies suggest aVon Hippel Lindau syndrome (VHL) is a dominantly inherited familial cancer syndrome predisposing to a variety of malignant and benign tumors. A germline mutation of VHL is the basis of familial inheritance of VHL syndrome. The protein encoded by VHL is a component of the protein complex that includes elongin B, elongin C, and cullin 2, and possesses ubiquitin ligase E3 activity. This protein is involved in the ubiquitination and degradation of hypoxia

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and murine studies suggest a role in tumor-associated tissue remodeling

The receptor TNFRSF9/4-1BB is absent from resting T lymphocytes but rapidly expressed upon antigenic stimulation

Autoantibodies against the protein may result in pulmonary transfusion reactions

these tips ensure minimal sample loss and contamination

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VHL Polyclonal Antibody, 20ul[BT-AP09520] Vortex Mixer and murine studies suggest aVon Hippel Lindau syndrome (VHL) is a dominantly inherited familial cancer syndrome predisposing to a variety of malignant and benign tumors. A germline mutation of VHL is the basis of familial inheritance of VHL syndrome. The protein encoded by VHL is a component of the protein complex that includes elongin B, elongin C, and cullin 2, and possesses ubiquitin ligase E3 activity. This protein is involved in the ubiquitination and degradation of hypoxia

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