LDH6B Polyclonal Antibody, 20ul Enzyme Activity Assays The protein encoded by EIF2AK2

The protein encoded by EIF2AK2 (eukaryotic translation initiation factor 2 alpha kinase 2) is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA

Functional studies indicate that this protein may be an important cofactor for BRCA2 in tumor suppression

and the modulatory beta subunit

The protein shows sequence similarity to the protein disulfide isomerase family

thus the RefSeq for this gene contains only two RRM domains

LDH6B Polyclonal Antibody, 20ul Enzyme Activity Assays The protein encoded by EIF2AK2Catalytic activity:(S) lactate + NAD(+) = pyruvate + NADH.,It is uncertain whether Met 1 or Met 50 is the initiator.,developmental stage: Higher expression level in adult testis as compared to 6 week old fetal testis.,pathway: Fermentation; pyruvate fermentation to lactate; (S) lactate from pyruvate: step 1 1.,Belongs to the LDH MDH superfamily. LDH family.,tissue specificity: Testis specific.,