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GALT2 Rabbit Polyclonal Antibody, 100ul Centrifuge Tube (Bottle) The protein encoded by SLC4A10

SKU: 28624641801

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GALT2 Rabbit Polyclonal Antibody, 100ul Centrifuge Tube (Bottle) The protein encoded by SLC4A10This gene encodes a member of the glycosyltransferase 2 protein family. Members of this family initiate mucin type O glycoslation of peptides in the Golgi apparatus. The encoded protein may be involved in O linked glycosylation of the immunoglobulin A1 hinge region. This gene may influence triglyceride levels and may be involved Type 2 diabetes as well as several types of cancer. Alternative splicing results in multiple transcript variants.

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Description

The protein encoded by SLC4A10 was initially identified as a sodium-driven chloride bicarbonate exchanger (NCBE) though there is now evidence that its sodium/bicarbonate cotransport activity is independent of any chloride ion countertransport under physiological conditions

Its activity is driven by the H+ electrochemical gradient of the lysosomal membrane

It encodes a single-pass type I membrane protein with multiple cysteine rich domains

giving rise to several mRNA species

which are encoded by distinct genes

GALT2 Rabbit Polyclonal Antibody, 100ul Centrifuge Tube (Bottle) The protein encoded by SLC4A10This gene encodes a member of the glycosyltransferase 2 protein family. Members of this family initiate mucin type O glycoslation of peptides in the Golgi apparatus. The encoded protein may be involved in O linked glycosylation of the immunoglobulin A1 hinge region. This gene may influence triglyceride levels and may be involved Type 2 diabetes as well as several types of cancer. Alternative splicing results in multiple transcript variants.

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