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SUMO3 Polyclonal Antibody, 50ul Sampling Tubes Defects in PEX3 are a

SKU: 28289199853

4.1
USD185.00 USD220.00

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SUMO3 Polyclonal Antibody, 50ul Sampling Tubes Defects in PEX3 are aThis gene encodes a member of the small ubiquitin related modifier (SUMO) family of eukaryotic proteins. The encoded protein is covalently conjugated to other proteins via a post translation modification known as sumoylation. Sumoylation may play a role in a wide variety of cellular processes, including nuclear transport, DNA replication and repair, mitosis, transcriptional regulation, and signal transduction. Alternatively spliced transcript variants

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Description

Defects in PEX3 are a cause Zellweger syndrome (ZWS)

This gene encodes a proline-rich protein that contains two A-T hook DNA binding domains

MIM 600075) and a set of TBP-associated factors (TAFs)

and MuvB protein (DREAM) complex to E2F target genes to repress transcription of multiple genes required for progression into S phase and mitosis

NLRP3 activates caspases 1 and 5

SUMO3 Polyclonal Antibody, 50ul Sampling Tubes Defects in PEX3 are aThis gene encodes a member of the small ubiquitin related modifier (SUMO) family of eukaryotic proteins. The encoded protein is covalently conjugated to other proteins via a post translation modification known as sumoylation. Sumoylation may play a role in a wide variety of cellular processes, including nuclear transport, DNA replication and repair, mitosis, transcriptional regulation, and signal transduction. Alternatively spliced transcript variants

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