DNA Ligase IV(Phospho Thr650) Polyclonal Antibody, 50ul Protein Modification cerebellin

cerebellin

|tissue specificity:Skeletal muscle| liver| heart and kidney

Growth arrest-specific 1 plays a role in growth suppression

which can cause excessive production of reactive oxygen species and cell stress

This gene has also been linked to diabetic nephropathy

DNA Ligase IV(Phospho Thr650) Polyclonal Antibody, 50ul Protein Modification cerebellinThe protein encoded by this gene is a DNA ligase that joins single strand breaks in a double stranded polydeoxynucleotide in an ATP dependent reaction. This protein is essential for V(D)J recombination and DNA double strand break (DSB) repair through nonhomologous end joining (NHEJ). This protein forms a complex with the X ray repair cross complementing protein 4 (XRCC4), and further interacts with the DNA dependent protein kinase (DNA PK). Both XRCC4