Rat Inhibitor of Nuclear Factor Kappa-B Kinase Subunit Beta, IKBKB ELISA Kit, 96T Gene Synthesis This inhibitor appears to be

This inhibitor appears to be species-specific

Component of the SCF(SKP2) complex containing SKP2

Belongs to the PRPF40 family

It encodes a type 1 membrane bound protease that is expressed in many tissues

Mutations in RRM2B have been associated with autosomal recessive mitochondrial DNA depletion syndrome

Rat Inhibitor of Nuclear Factor Kappa-B Kinase Subunit Beta, IKBKB ELISA Kit, 96T Gene Synthesis This inhibitor appears to beSerine kinase that plays an essential role in the NF kappa B signaling pathway which is activated by multiple stimuli such as inflammatory cytokines, bacterial or viral products, DNA damages or other cellular stresses. Acts as part of the canonical IKK complex in the conventional pathway of NF kappa B activation and phosphorylates inhibitors of NF kappa B on 2 critical serine residues. These modifications allow polyubiquitination of the inhibitors and