Lamin B1 Polyclonal Antibody, 100ul[BT-AP04935] General Lab Use It is highly conserved in

It is highly conserved in vertebrates and most abundantly expressed in the brain

Gene Ontology (GO) annotations related to PJA2 include ligase activity and protein kinase A catalytic subunit binding

Belongs to the vinculin/alpha-catenin family

Alternatively spliced transcript variants have been observed but the full-length nature of only one has been determined

The genomic region is also rich in Alu repetitive sequences

Lamin B1 Polyclonal Antibody, 100ul[BT-AP04935] General Lab Use It is highly conserved inLMNB1 encodes one of the two B type lamin proteins and is a component of the nuclear lamina. A duplication of LMNB1 is associated with autosomal dominant adult onset leukodystrophy (ADLD). Alternative splicing results in multiple transcript variants.