Vav1 Polyclonal Antibody, 100ul[BT-AP09488] Cell Separation and Collection The protein encoded by this

The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M)

Src family tyrosine kinase associates with the p85 subunit of phosphatidylinositol 3-kinase and interacts with the fyn-binding protein

but this gene encodes proteins with only a single BIR domain

allelic exclusion at the Ig heavy chain gene locus

Created with a 0

Vav1 Polyclonal Antibody, 100ul[BT-AP09488] Cell Separation and Collection The protein encoded by thisVAV1 is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. The Proto oncogene vav is important in hematopoiesis, playing a role in T cell and B cell development and activation. The encoded protein has been identified as the specific binding partner of Nef proteins from HIV 1.