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PDK1 Polyclonal Antibody, 100ul[BT-AP07028] Shakers Nucleosomes wrap and compact DNA

SKU: 24128307322

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PDK1 Polyclonal Antibody, 100ul[BT-AP07028] Shakers Nucleosomes wrap and compact DNAPyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Multiple alternatively spliced

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Description

Nucleosomes wrap and compact DNA into chromatin| limiting DNA accessibility to the cellular machineries which require DNA as a template

Expressed in fetal liver

mutations in this gene can cause the autosomal recessive form of Robinow syndrome

and inactivated by two groups of GTPase-activating proteins (GAPs)

This gene is expressed at high levels in primary neutrophils and primary monocytes

PDK1 Polyclonal Antibody, 100ul[BT-AP07028] Shakers Nucleosomes wrap and compact DNAPyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Multiple alternatively spliced

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