IGF-I Receptor beta(Phospho-Tyr1316) Rabbit Polyclonal Antibody, 50ul Deep Well Plates This gene has an ORF

This gene has an ORF encoding a 141 aa polypeptide which is similar to the delta globins found in reptiles and birds

Its design is also resistant to harsh chemicals

This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system

causing detachment from microtubules

The different transcripts result from the use of alternate transcription initiation sites

IGF-I Receptor beta(Phospho-Tyr1316) Rabbit Polyclonal Antibody, 50ul Deep Well Plates This gene has an ORFThis receptor binds insulin like growth factor with a high affinity. It has tyrosine kinase activity. The insulin like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have