NuMA(Phospho-Thr2055) Rabbit Polyclonal Antibody, 20ul Diagnostic Probes & Oligos ART1 (ADP-ribosyltransferase 1) was previously

ART1 (ADP-ribosyltransferase 1) was previously designated ART2

which is required for for the IL-1 induced activation of nuclear factor kappaB and MAPK8/JNK

2007 [PubMed: 17499941])

Alternatively spliced transcript variants encoding the same protein have been found for this gene

The protein encoded by this gene belongs to the Kruppel family of C2H2-type zinc finger proteins

NuMA(Phospho-Thr2055) Rabbit Polyclonal Antibody, 20ul Diagnostic Probes & Oligos ART1 (ADP-ribosyltransferase 1) was previouslyThis gene encodes a large protein that forms a structural component of the nuclear matrix. The encoded protein interacts with microtubules and plays a role in the formation and organization of the mitotic spindle during cell division. Chromosomal translocation of this gene with the RARA (retinoic acid receptor alpha) gene on chromosome 17 have been detected in patients with acute promyelocytic leukemia. Alternative splicing results in multiple