Trypsin-3 Polyclonal Antibody, 20ul Petri Dishes Alternate splicing of mouse NLRP3

Alternate splicing of mouse NLRP3 generates additional isoforms that lack either LRR2 and 3

Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders

plays a role in innate immunity and inflammation

GPRC5A may play a role in embryonic development and epithelial cell differentiation

They are responsible for the generation and propagation of action potentials in neurons and muscle

Trypsin-3 Polyclonal Antibody, 20ul Petri Dishes Alternate splicing of mouse NLRP3PRSS3 encodes a trypsinogen, which is a member of the trypsin family of serine proteases. This enzyme is expressed in the brain and pancreas and is resistant to common trypsin inhibitors. It is active on peptide linkages involving the carboxyl group of lysine or arginine. This gene is localized to the locus of T cell receptor beta variable orphans on chromosome 9. Four transcript variants encoding different isoforms have been described for this gene.