MuSK Monoclonal Antibody, 50ul Centrifugal Filter The activity of this protein

The activity of this protein is stimulated by phosphoinosides and inhibited by phosphatidylcholine

which is a common motif in proteins involved in chromatin remodeling

This protein acts as part of a multisubunit complex which includes histone deacetylases to modify chromatin structure that prevents basal transcriptional activity of target genes

Deletion of PIAS1 leads to inhibition of interferon-inducible genes and increased protection against infection

which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides

MuSK Monoclonal Antibody, 50ul Centrifugal Filter The activity of this proteinThis gene encodes a muscle specific tyrosine kinase receptor. The encoded protein may play a role in clustering of the acetylcholine receptor in the postsynaptic neuromuscular junction. Mutations in this gene have been associated with congenital myasthenic syndrome. Alternatively spliced transcript variants have been described.