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CD6 Polyclonal Antibody, 50ul[BT-AP02235] Digital Burette This gene is expressed in

SKU: 22102413783

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CD6 Polyclonal Antibody, 50ul[BT-AP02235] Digital Burette This gene is expressed inCRKL encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS dependent fashion. It is a substrate of the BCR ABL tyrosine kinase, plays a role in fibroblast transformation by BCR ABL, and may be oncogenic.

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Description

This gene is expressed in both normal and tumor cells

and appears to act as a negative regulator of cytoskeletal organization leading to loss of adhesion

and can bind RNA

Activated by diacylglycerol (DAG) (By similarity)

45 µm Pore Size and PES Membrane ensure reliable filtration

CD6 Polyclonal Antibody, 50ul[BT-AP02235] Digital Burette This gene is expressed inCRKL encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS dependent fashion. It is a substrate of the BCR ABL tyrosine kinase, plays a role in fibroblast transformation by BCR ABL, and may be oncogenic.

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